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Ionis Pharmaceuticals, Inc. (IONS) Operating Income 2021–2025

DATA UPDATED 2026-07-09

Ionis Pharmaceuticals, Inc. annual operating income for fiscal 2025 was -$382 million, an increase of 19.7% from -$475 million in fiscal 2024. All figures are reported results from public filings — no estimates or projections.

IONS Annual Operating Income

Operating Income (annual)2025-12-312024-12-312023-12-312022-12-312021-12-31
Operating Income (EBIT)($382M)($475M)($354M)($410M)—

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

IONS Quarterly Operating Income

Operating Income (quarterly)2026-03-312025-12-312025-09-302025-06-302025-03-31
Operating Income (EBIT)($118M)($214M)($160M)$140M($147M)

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

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