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Ionis Pharmaceuticals, Inc. (IONS) Financial History

4 years of revenue, earnings, cash-flow and balance-sheet history from public filings.

Healthcare · Biotechnology · DATA UPDATED 2026-07-09

Ionis Pharmaceuticals, Inc. (IONS) operates in the Biotechnology industry and is headquartered in Carlsbad, United States with about 1,402 employees. Its market capitalization is roughly $11 billion. In the fiscal year ended 2025-12-31, IONS reported $944M in revenue and ($381M) in net income.

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States.

Interactive charts & full statements → Open the IONS valuation workbench →

IONS Revenue & Earnings History — Annual Income Statement

Income statement2025-12-312024-12-312023-12-312022-12-312021-12-31
Total Revenue$944M$705M$788M$587M
Gross Profit$928M$694M$778M$573M
Operating Income (EBIT)($382M)($475M)($354M)($410M)
Net Income($381M)($454M)($366M)($270M)

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

IONS Quarterly Revenue & Earnings — Last 8 Quarters

Quarterly income statement2026-03-312025-12-312025-09-302025-06-302025-03-31
Total Revenue$246M$203M$157M$452M$132M
Gross Profit$243M$195M$154M$448M$130M
Operating Income (EBIT)($118M)($214M)($160M)$140M($147M)
Net Income($92M)($229M)($129M)$124M($147M)

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

IONS Free Cash Flow History

IONS Balance Sheet History

Balance sheet2025-12-312024-12-312023-12-312022-12-312021-12-31
Total Assets$3.5B$3.0B$3.0B$2.5B
Total Liabilities$3.0B$2.4B$2.6B$2.0B

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

Quarterly statements, profitability ratios, price history, insider activity and institutional holders are in the interactive IONS viewer.

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