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Spyre Therapeutics, Inc. (SYRE) Operating Income 2022–2025

DATA UPDATED 2026-07-10

Spyre Therapeutics, Inc. annual operating income for fiscal 2025 was -$220 million, a decrease of 5.3% from -$209 million in fiscal 2024. All figures are reported results from public filings — no estimates or projections.

SYRE Annual Operating Income

Operating Income (annual)2025-12-312024-12-312023-12-312022-12-31
Operating Income (EBIT)($220M)($209M)($129M)($85M)

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

SYRE Quarterly Operating Income

Operating Income (quarterly)2026-03-312025-12-312025-09-302025-06-302025-03-312024-12-31
Operating Income (EBIT)($76M)($57M)($57M)($52M)($54M)—

USD; $M / $B as marked. Newest period first. Source: public company filings (via Yahoo Finance aggregation).

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